EXPLORING THE POTENTIAL OF A STRUCTURAL ALPHABET-BASED TOOL FOR MINING MULTIPLE TARGET CONFORMATIONS AND TARGET FLEXIBILITY INSIGHT.

Exploring the potential of a structural alphabet-based tool for mining multiple target conformations and target flexibility insight.

Protein flexibility is often implied in binding with different partners and is essential for protein function.The growing number of macromolecular structures in the Protein Data Bank entries and their redundancy has become a major source of structural knowledge of the protein universe.The analysis of structural variability through available redunda

read more



Interventions for oropharyngeal dysphagia in acute and critical care: a protocol for a systematic review and meta-analysis

Abstract Background Oropharyngeal dysphagia or swallowing difficulties are common in acute care and critical care, affecting 47% of hospitalised frail elderly, 50% of acute stroke patients and approximately 62% of critically ill patients who have been intubated and mechanically ventilated for prolonged periods.Complications of dysphagia include asp

read more